Co-carcinogenic Effect of Retinyl Acetate on Forestomach Carcinogenesis of Male F344 Rats Induced with Butylated Hydroxyanisole
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چکیده
منابع مشابه
the effect of aqueous extract of garlic on formalin-induced pain in male rats
چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولInduction of cell proliferation in the forestomach of F344 rats following subchronic administration of styrene 7,8-oxide and butylated hydroxyanisole.
The question addressed was whether stimulation of cell proliferation could be responsible for tumor induction in the forestomach by styrene 7,8-oxide (SO). Male F344 rats were treated for 4 weeks with 0, 137, 275, and 550 mg/kg SO by p.o. gavage 3 times/week. Positive controls received 0, 0.5, 1, and 2% butylated hydroxyanisole (BHA) in the diet for 4 weeks. Twenty-four h before termination of ...
متن کاملInduction of Cell Proliferation in the Forestomach of F344 Rats FoUowing Subchronic Administration of Styrene 7,8-0xide and Butylated Hydroxyanisole
for the 2% diet). to protein in vivo (20, 21). lt is possible, therefore, that SO and BHA were carcinogenic in the forestomach via a similar "nongenotoxic" mechanism of action, i.e., the stimulation 01' cell division induced by cytotoxicity and regenerative hyperplasia. This mechanism has been postulated for various forestomach carcinogens (22). BHA was demonstrated to have a strong hyperplasio...
متن کاملInduction of Cell Proliferation in the Forestomach of F344 Rats Following Subchronic Administration of Styrà ̈ne7,8-Oxide and Butylated Hydroxyanisole
The question addressed was whether stimulation of cell proliferation could be responsible for tumor induction in the forestomach by styrà ̈ne 7,8-oxide (SO). Male F344 rats were treated for 4 weeks with 0, 137, 275, and 550 mg/kg SO by p.o. gavage 3 times/week. Positive controls received 0, 0.5, 1, and 2% butylated hydroxyanisole (BHA) in the diet for 4 weeks. Twenty-four h before termination of...
متن کاملDifferent Modifying Response of Butylated Hydroxyanisole, Butylated Hydroxytoluene, and Other Antioxidants in A'jjV-Dibutylnitrosamine Esophagus and Forestomach Carcinogenesis of Rats1
The modifying effects of antioxidants were examined in a carcinogenesis system after \, V-ililnilvlniinisamiiic treatment. Male F344 rats were given 0.05% V, Vdilnilylnhrosarnmiin their drinking water for 4 wk and then treated with basal diet containing 2% butylated hydroxyanisole (BHA), 1% butylated hydroxytoluene (BHT) with 7 ppm vitamin K, 0.8% ethoxyquin, 5% sodium L-ascorbate, 57. sodium e...
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ژورنال
عنوان ژورنال: Japanese Journal of Cancer Research
سال: 1988
ISSN: 0910-5050
DOI: 10.1111/j.1349-7006.1988.tb01594.x